Supplements are best used in situations where an individual is unable to get their nutrients from their diet. Perhaps an individual has an allergy or intolerance, for example lactose. They are unable to consume milk products which in turn limits their ability to get sufficient calcium and vitamin D from their diet. In that case, a supplement makes sense.
Research has been conducted on the potential use of deer antler velvet for healing of wounds. In Russia (Arapov, 1969), Pantocrin was administered to patients with surgical and internal wounds. The study reported that there were a number of positive effects, including the normalization of arterial pressure, reduction in surgical complications, and becoming active quicker. In tests on rats (Wang, 1985), bone fracture repair was accelerated. A recent study by Bubenik found that antler helped heal epidermal wounds in rats. In another study by Takikawa, et al., researchers reported observing new bone formation following experimental whiplash injuries in rabbits. Pretreatment in rats reduced cell degradation and improved recovery times from extreme temperature and electric shock exposure. 

Powdered velvet antler is available in capsule form from health shops. As a general tonic and to fight fatigue, the recommended dosage is usually 1 or 2 capsules (250 to 350 milligrams each) per day. For conditions such as osteoarthritis, higher doses may be used under supervision of a health practitioner. The effects of velvet antler gradually accumulate and are typically seen 8 to 12 weeks.

There must be a reason to is use and a booming world industry that garners the attention of several researchers and scientist in many countries. Modern understanding has greatly advanced our knowledge of velvet antler. We know by its composition and the knowledge of the structure and function of the plenitude of constituents which work together, like a symphony, to create an efficacious supplement that yields a multitude of benefits.
Currently, one study that induced a fracture unto a rat bone and injected 20mg/kg of Velvet Antler polypeptides into the area every other day for 7 weeks noted that fracture healing rate was dose-dependently increased at weeks 4-7 relative to control and that the bone loading weight was increased following rehabilitation with 10mg/kg (60.7%) and 20mg/kg (93% more than control) after 7 weeks.[29] An in vitro study suggested that this was due to a concentration-dependent mitogenic activity on osteoblastic precursors and chondrocytes.[29]
Deer antler velvet's effects on cell growth and repair have been investigated in several areas. Deer antler velvet may be a natural source of hormones for those seeking aid to muscle growth and development. Research has identified various growth factors in deer antler velvet including IGF-1 (insulin–like Growth Factor-1), IGF-2 (insulin–like Growth Factor-2), and EGF (Epidermal Growth Factor).
One study[14] (duplicated in Medline[15]) that used a water extract of Velvet Antler at 50-200mg/kg failed to inhibit the pain killing effect of Morphine yet reduced the rate at which rats became tolerant to Morphine over the course of 6 days when taken an hour prior to Morphine each day.[14] Rats who were given Velvet Antler prior to Morphine also experienced 26.6-36.6% less withdrawal (dose-dependent) and reduced reverse tolerance and dopamine receptor supersensitivity relative to morphine control.[14]

In Asia, velvet antler is dried and sold as slices, or as a powder which may be boiled in water, usually with other herbs and ingredients, and consumed as a medicinal soup.[6] In the traditional commercial trade of Korea and China, whole stick antler velvet is divided into three sections based upon their supposed properties. Although there is an absence of uniform standardization, these sections are known as the wax piece (uppers or tips), the blood piece (middles), and the bone piece (bottoms): the wax piece may be marketed as a growth tonic for children, the blood piece supposedly for joint and bone health, and the bone piece supposedly for calcium deficiency and geriatric needs.[2][5][9] Early commercial activity in Russia between the 1930s and 1980s led to the production of an alcohol extract from deer antler velvet marketed under the Russian drug trade name Pantocrin (also pantocrine or pantokrin).[10][11]
In September, 2013, the headquarters of S.W.A.T.S. was raided and ordered to be shut down by Alabama's attorney general citing "numerous serious and willful violations of Alabama’s deceptive trade practices act".[30][31] Among the violations were "claims that the company made about a number of products that were unsupported by scientific research. Some of these products were marketed as 'dietary supplements.'" [32] The assistant Alabama attorney general "says that Deer Antler Spray is dangerous and its sellers are law-breakers." [33]
More recent tests (Slievert, 2003) confirm deer antler velvet’s effects on muscle strength and endurance. In a randomized, double blind, placebo controlled experiment, 18 males entered a 10 week strength training program. Those who took deer antler velvet showed an increase in maximal aerobic capacity, an increase in strength in the bench press and leg squat, and decrease in body fat relative to the placebo group.
"Here's my advice to you. Find a product that contains the right kind of high quality grass fed whey protein isolate and is sweetened with the right kind of sweetener. I did want to give a shout out to Antler Farms® who has a nice, high quality New Zealand Whey Protein Isolate. They've gone the extra mile in a lot of different directions. I like to give shout outs to companies that I think deserve it and actually care about our health."*
There is an increasing amount of scientific evidence supporting the benefits of deer antler velvet from decades of research carried out in Russia, Korea, China, Japan, Australia and New Zealand. This research has given credibility to deer antler velvet’s traditional usage and validated recommendations for its inclusion as an everyday health supplement. Almost 250 papers have been published since 1930 on the manufacture, composition and biochemical effect of deer antler velvet. Studies on deer antler velvet and the corresponding findings are described below.
I have not felt much differently since I started taking the deer antler however I did notice that when I do the arm bike I can do it faster and longer without weakness. Now you would say so big deal. For me that is a huge difference that I am tracking. I NEVER was good on the arm bike even when I was in shape it felt more labored. I am horribly out of shape for me and yet I can do this with comfortable effort. I also have taken the REM product Anna Nova health offers. Now this is where I DO notice a difference again but much more that the daily effect. My sleep has regulated to where most nights I have been able to sleep at least 5-6hrs straight. I have done that in the past. What I notice is that my body actually FEELS rested like i went into a deeper sleep. I have tried everything to sleep. Some things that are suppose to help actually work the opposite. Most all drugs have horrible effects on me and I NEVER wake up rested. I wake up foggy doppy and irritable-if I sleep. I have to say something about this works. Maybe it effects my body chemistry in manner it needs. I don’t know but its not because I WANT it to work. I have taken all this stuff tried all this stuff expecting failure. I have not slept well my whole life. Since the head injury even if I do sleep I’m not rested nor do I feel that my body relaxes. Since I have taken this after two weeks I noticed a big difference. 5hrs for most people is horrible- for me its good 6 is great and my ideal sleep. I am staying on it for another couple months to see if I feel or notice any other differences. As far as helping “heal” my body WIM hof cold exposure works the best for my brain so far. Brain injury/neck injury people are different from those without. We have dysfunctional nerves neurotransmitters and path waves that cause things to happen that we need to find other ways to fix. Drs just don’t listen and pay attention to people who are in tune with their bodies. Its too bad cause they could learn a lot from us.
A 2014 study published in Evidence Based Complimentary and Alternative Medicine tested whether or not deer antler extract would have an effect on fatigue in mice who were led to swim distances. The findings suggested that deer antler “might increase the muscle strength through the upregulation of genes responsible for muscle contraction and consequently exhibited the anti-fatigue effect in mice.” Deer antler seems to have a positive effect on genes involved in nine different signaling pathways that affect muscles, endurance and fatigue. These include GnRH signaling pathway and insulin signaling pathways, in addition to levels of troponins. (8) Deer antler may contribute to increases in muscle strength by increasing Tpm2 expression. This affects how muscles take up proteins and repair themselves. Other studies show some evidence that deer antler extract helps prevent muscle fatigue by activating the lactate dehydrogenase activities and reducing the levels of blood lactic acid and serum urea nitrogen.
The message was from Neema Yazdani. Some of you might recognize Neema’s name from my most recent book, The Men’s Health Big Book: Getting Abs. Neema was a test subject that epitomized the great results you could receive with the program. As a guy that had tried just about everything during the last 12 years, Neema dropped body fat and added muscle with a simpler approach included in the book.
One study in men given 1.5g Velvet Antler for 11 weeks noted that intake of Velvet Antler was associated with a greater improvement in peak torque (30+/-21% more than baseline vs. placebo increasing 13+/-15%) and average power (21+/-19% vs. 7+/-12%) as assessed by leg extension; the authors noted that other parameters suggestive of power improvement (such as endocrine improvements or erythropoesis) did not occur and noted that replication is needed.[26] The lack of aerobic improvement noted in this study is contrasted by another study using 2,700mg of Velvet Antler (two doses of 1,350mg daily for 10 weeks) which improved VO2 max by 9.8%, although this study had a remarkably high dropout rate of 44% which precludes conclusions that can be drawn.[27]
A Russian study indicated that the amino acids, polypeptides and other compounds found in antler increased the survival rate of mice with cancerous tumors as much as 40 percent. In addition, a study conducted by the East-West Research Institute in Korea found that deer antler velvet appears to increase neutrophil levels in mice, which boost the body’s ability to fight injuries and disease. The mice with tumors lost less weight and suffered lower levels of kidney damage than those treated with drugs.
While consumers wanted more information on the product. Let’s not forget the supplement industry is a multi-billionaire dollar business. And if Ray used the product then it must be legit, right? That’s what the immediate response in supplement sales would have you believe, as ESPN business reporter Darren Rovel reported that purchases skyrocketed within 24 hours of the report.
Being a former collegiate athlete, I’m no stranger to working out. When a former teammate of mine started talking about this new, state of the art, health product and the effects he was getting from it, it peaked my interest needless to say. I remember him continually saying that I’d have to try it to believe what it does for you. Wow, I must now say that I know what he means (and then some)! First of all, this IGF-1 Plus™ Formula did have some impressive results for me in my workouts. It’s not only helped my strength, but it seems that I especially notice a difference in my joints and my recovery time. Since I lift with heavy weights, my joints used to ache after working out, but they no longer do! My endurance also has really improved as well. I’ve actually doubled the time and distance that I was doing before (and I’ve only been on it for a little over a month)! An unexpected (but much welcomed) improvement that has been incredible is in how clearly I’ve been able to think and I feel very little stress anymore. It almost like someone put a micro-computer chip in my brain that makes it work much more efficiently without trying nearly as hard. It’s one of those things that you have to try to really believe it (trust me, it has done much more than I expected it to). I look forward to turning a friend of mine on to it, since he’s a personal trainer and trains professional athletes! Thanks, Dr. Duarte. I plan to use your IGF-1 Plus™ from now on, and will stock up so I don’t run out!
This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. This product may be unsafe when used before surgery or other medical procedures. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age.
Unfortunately, the potential problems with IGF would seem to negate any of these theoretical benefits.  It has been shown that improper use of hormones such as dehydroepiandrosterone (DHEA), androstenedione, and human growth hormone may increase the risk for development of prostate cancer or promote the growth of existing prostate cancer by raising IGF-1 levels.  Therefore, men who are taking supplements with IGF in it (or those that raise IGF levels) could theoretically be putting themselves at an increased risk for prostate cancer.  Again, it hasn’t been rigorously studied so it’s impossible to know for sure, but if you have any risk factors for prostate cancer, it’s probably best to avoid taking this supplement.  
Companies attributing health claims from using dietary supplements of velvet antler have received warning letters from the US Food and Drug Administration (FDA) concerning the sale of encapsulated powders connected to their marketing claims.[12] The claims were in violation of the United States Food, Drug and Cosmetic Act [21 USC/321 (g)(1)][36] because they "establish the product as a drug intended for use in the cure, mitigation, treatment, or prevention of disease" when velvet antler has no such scientific evaluation. Additionally stated by the FDA, velvet antler was "not generally recognized as safe and effective for the referenced conditions" and therefore must be treated as a "new drug" under Section 21(p) of the Act. New drugs may not be legally marketed in the United States without prior approval of the FDA.[12][14][15][16][17] As of 2018, it is legal to sell velvet antler powder, extract or spray in the U.S. as a dietary supplement as long as no disease treatment claims are made and the label bears the FDA disclaimer: "This product has not been evaluated by the FDA. It is not intended to diagnose, treat, cure or prevent any disease."
I took red mountain deer velvet and it really messed my stomach up. I now have cramps and bloating all the time plus it feels like my stomach shrank…I can’t eat like I used to. It was a big mistake to take that stuff. Do you know of any way I can get my stomach back to normal??? Can you recommend someone who knows a lot about deer velvet?? I have been suffering terribly since I took that junk…it’s been about 2 years now!!!! My stomach has never been the same since I took that poison!!

One of the leading companies in the world that manufacturers deer antler spray is called Nutronics Labs. According to information posted on their website, they have been making deer antler supplements for two decades. They state that their deer antler products range in concentration/strength from about 25,000ng (nanograms)–200,000ng of IGF-1. According to studies done by Nutronics Labs, deer antler powders appear to be less concentrated with IGF-1. They also may be poorly absorbed compared to deer antler extract.
The product smells like lemon-scented cleaner and bears a resemblance to murky pond water. I hesitantly tried the stuff and found it surprisingly palatable, with a lemon taste, but not too sour and slightly sweet. The directions say to take 14 drops under the tongue, three times a day, but I stopped after one dose — so I probably don't have a good chance of reaping the benefits, if there are any.
Immortal Antler Velvet Gold is the Mercedes of antler velvet extracts. It is the only all-natural 43:1 extract that contains a powerful blend of growth factors in a naturally occurring matrix. These naturally occurring growth factors are involved in every cellular function in the human body, from metabolism to immune response. Immortal Antler Velvet Gold is the only all-natural proprietary matrix to deliver up to 100 mcg’s of IGF-1 per bottle, in addition to the full growth factor matrix. Delivering a full range of growth factors at an alarming 43:1 ratio means there is no stronger formula on the market today. This ratio means it requires 43 lbs of velvet antler tips to create 1 lb of this complete formula. It is extracted in organic grape alcohol and bottled in miron violet glass for maximum absorption and effectiveness.
Keeping true to our original Deer Antler Spray formula, Deer Antler Velvet Extract HERS is all-natural and contains the same amount of Deer Antler Velvet as the original, coming to us straight from red deer in New Zealand. Like the original, our new product is high in the growth hormone IGF-1. This new spray, however, is testosterone free and contains: collagen type II, biotin, green tea, and epimedium, all of which have benefits specially geared toward female athletes. Epimedium, known in Chinese medicine as “yin yang huo”, has the same effect as estrogen, can increase libido, and produce osteoblasts, the cells that secretes the matrix for bone formation. This promotes strong bones, and aids in the prevention of osteoporosis. Collagen, is a protein that forms the strong, flexible white fibers of the body's bone, cartilage, and connective tissue, and is vital for tissue regeneration. Biotin can speed up metabolism, improve glucose levels, and improve brittle nails. Green tea, is one of nature's most powerful antioxidants, and has been linked to cancer prevention, Alzheimer's prevention, the prevention of obesity, and countless other health benefits.
Velvet Antler is a supplement derived from powdered or crushed antlers, most commonly from deer (and thus referred to as Deer Velvet Antler) although Elk have also been used. They have been used in Traditional Chinese Medicine.[1] The base of the antler is referred to as Cervus (in reference to deers), Lu Jiao Pan, Zhen Zhu Pan, as well as Lu Hua Pan and appears to have been traditionally used for cardiovascular disease, gynecological problems, immunological deficiencies, blood cancers, tissue repair and health promotion.[1] The specific part used is the antler base; when the antler is sawed off the base temporarily remains until the regeneration of the new antler pushes it off which occurrs occasionally in the wild. Traditional usage involves using the base and macerating it in wine or decocting it with water for oral consumption.[1]
According to an article in Sports Illustrated, Lewis spoke by telephone after his injury with Mitch Ross, co-owner of the supplement company S.W.A.T.S. (Sports with Alternatives to Steroids) to ask about treatments that could speed his recovery. Sports Illustrated reported that among Ross’ recommendations were deer antler pills to “rebuild your brain via your small intestines.” In addition to recommending the pills, Ross reportedly also told Lewis to spray deer antler extract under his tongue. Lewis has denied following this advice, and Ravens’ management has said that the star player has never flunked a drug test.
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