1g of Velvet Antler taken daily for 12 weeks in otherwise healthy adult men has failed to significantly alter serum testosterone levels, either total or free testosterone. Another study in otherwise healthy men has also failed to find such an effect on the endocrine profile, with 11 weeks of 1.5g supplementation failing to alter serum testosterone and a lack of effects also noted after 10 weeks of 560mg in males and females who performed a consistent rowing regimen.
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Deer antler velvet is the tissue that covers the bone and cartilage that develop into deer (and elk) antlers. It has been harvested for centuries and used traditionally to increase strength, boost the immune system, and counter the effects of stress. Now it’s promoted to improve athletic performance; raise testosterone levels to increase sex drive, fertility and erectile function in men; as well as to reduce the signs of aging and treat problems ranging from high cholesterol, high blood pressure, asthma and osteoporosis to migraine headaches, indigestion, and many more.
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A systemic review on human interventions makes note of a study conducted on patients of osteoarthritis (Edelman et al. 2000; cannot be located online) which found improvements in joint pain symptoms relative to baseline in the Velvet Antler group and not placebo, although a lack of information on blinding and randomization precludes results that can be drawn from this study.