A 2014 study published in Evidence Based Complimentary and Alternative Medicine tested whether or not deer antler extract would have an effect on fatigue in mice who were led to swim distances. The findings suggested that deer antler “might increase the muscle strength through the upregulation of genes responsible for muscle contraction and consequently exhibited the anti-fatigue effect in mice.” Deer antler seems to have a positive effect on genes involved in nine different signaling pathways that affect muscles, endurance and fatigue. These include GnRH signaling pathway and insulin signaling pathways, in addition to levels of troponins. (8) Deer antler may contribute to increases in muscle strength by increasing Tpm2 expression. This affects how muscles take up proteins and repair themselves. Other studies show some evidence that deer antler extract helps prevent muscle fatigue by activating the lactate dehydrogenase activities and reducing the levels of blood lactic acid and serum urea nitrogen.
But when it comes to sprays or pills, there’s little evidence that deer antler offers performance enhancing benefits of any kind, says Alan Rogol, M.D., an endocrinologist at the University of Virginia. Rogol is also part of a small team of doctors that assists anti-doping agencies in determining if and when athletes can use certain controversial substances.

Studies have found that deer antlers themselves contain a highly concentrated amount of essential trace minerals, fatty acids, amino acids and growth factors that can all support the immune system. This includes the gastrointestinal tract, where the majority of the immune system is found. Antlers contain minerals such as: calcium, phosphorus, magnesium, iron, potassium and sodium in addition to numerous minor components.
Tanejeva also tested the effect of deer antler velvet in athletes running three kilometer races. In the experiment, 50 men ran the distance and their completion time was recorded. Deer antler velvet extract was administered to half of the runners and the participants repeated the race.  The group receiving the Pantocrin completed the subsequent race in a faster average time.
Immortal Antler Velvet Silver is a less potent form of antler velvet than the Gold. It’s the only all-natural 19:1 extract that contains a powerful blend of growth factors in a naturally occurring matrix, and the only all-natural proprietary matrix to deliver up to 45 mcg’s of IGF-1 per bottle, in addition to the full growth factor matrix. Delivering a full range of growth factors at a 19:1 ratio means it requires 19 lbs of velvet antler tips to create 1 lb of this complete formula. Immortal Antler Velvet Silver is extracted in organic grape alcohol and bottled in miron violet glass for maximum absorption and effectiveness.
Even more intriguing is how the stags manage to regrow their antlers. Scientists have found stem cells at the bases of antlers’essentially ‘blank’ cells that can develop into many different types of cell, such as a skin cell or a cartilage cell. If they could find out what triggers the stem cells and controls their development into antlers, the knowledge could be applied to the regeneration of human limbs and organs. Scientists know that the shedding is initiated by a fall in the hormone testosterone, a change linked to an increase in day length, and they think oestrogen may be a key cellular regulator. However, much more research on a molecular level is required to unravel what is clearly an intricate process.
As men and women get older, they naturally start producing less Human Growth Hormone (HGH). So levels of IGF-1 also decline with age. The liver produces IGF-1 when HGH is released.  HGH is converted to IGF-1. Aside from someone’s age, IGF-1 levels will vary depending on a person’s sex (men generally have more), level of activity, their diet, genetics and lifestyle.
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The IGF-1 in deer antler velvet can help increase the body's natural healing by affecting cell repair and growth. When an injury or surgery occurs that leaves a wound on the body, the wound is healed naturally by the cells which line the wound. Those cells multiply and rejoin over time. Using deer antler velvet can help promote faster cell repair and growth so that the wound can heal at a faster rate which means less time being injured or sore.


An acute dose of 2,000mg/kg Deer Velvet Antler to rats (human equivalent dose of 320mg/kg) has failed to show toxic signs over 14 subsequent days of observation, and a 90 day trial with daily dosing of 1,000mg/kg did not show any significant toxicological symptoms of haemotological signs; a decrease in liver weight was noted in males, but under histological examination it appeared to be benign.[38] Another rat toxicological study using 10% of the diet as Deer Velvet Antler during gestation and after birth noted that there were no apparent teratogenic effects on the rat pups and that serum AST (indicative of liver damage) was actually decreased 50% relative to control with no effect on γ-GT (another liver enzyme).[30]

Ultimately it is too early in the testing process for our experts to be able to recommend Deer Antler Velvet Spray as either safe or effective as a joint health supplement. It is more possible it is effective as a male libido enhancer than as a nutritional supplement, and there is little reason to think that Deer Antler Velvet Spray could do much to actually contribute to the health of the body’s connective tissues. It does not have any anti-inflammatory agents to fight joint pain, there is only the smallest amount of glucosamine and chondroitin, and finally the potential for negative consequences is too high for our team to be able to encourage our readers to consume this product.
In Asia, velvet antler is dried and sold as slices, or as a powder which may be boiled in water, usually with other herbs and ingredients, and consumed as a medicinal soup.[6] In the traditional commercial trade of Korea and China, whole stick antler velvet is divided into three sections based upon their supposed properties. Although there is an absence of uniform standardization, these sections are known as the wax piece (uppers or tips), the blood piece (middles), and the bone piece (bottoms): the wax piece may be marketed as a growth tonic for children, the blood piece supposedly for joint and bone health, and the bone piece supposedly for calcium deficiency and geriatric needs.[2][5][9] Early commercial activity in Russia between the 1930s and 1980s led to the production of an alcohol extract from deer antler velvet marketed under the Russian drug trade name Pantocrin (also pantocrine or pantokrin).[10][11]
L-Arginine: An amino acid usually found in red meats that is important for the body’s ability to manufacture proteins. L-Arginine has been used to treat conditions like high blood pressure, congestive heart failure, blocked arteries, and erectile dysfunction. L-Arginine is safe for most people, however it should not be taken by women that are pregnant or breastfeeding.
Shake bottle before each use. Then take 12 drops under the tongue twice a day. Hold the liquid under your tongue for 20 seconds before swallowing. This allows the formula to penetrate through your endocrine glands. Then the active molecules are released directly into your bloodstream. This is how Nutronics Labs' liposome technology is able to deliver an enhanced bioavailability!
Tanejeva also tested the effect of deer antler velvet in athletes running three kilometer races. In the experiment, 50 men ran the distance and their completion time was recorded. Deer antler velvet extract was administered to half of the runners and the participants repeated the race.  The group receiving the Pantocrin completed the subsequent race in a faster average time.
Insulin-like Growth Factor 1 (IGF-1) is an anabolic molecule which appears to induce growth of the antlers themselves,[31][32] although testosterone may be the primary growth factor.[33] Currently, there is no evidence that serum IGF-1 is increased following Velvet Antler ingestion with one study using 1.5g of Velvet Antler for 11 weeks failing to increase serum IGF-1.[26]
In Asia, velvet antler is dried and sold as slices, or as a powder which may be boiled in water, usually with other herbs and ingredients, and consumed as a medicinal soup.[6] In the traditional commercial trade of Korea and China, whole stick antler velvet is divided into three sections based upon their supposed properties. Although there is an absence of uniform standardization, these sections are known as the wax piece (uppers or tips), the blood piece (middles), and the bone piece (bottoms): the wax piece may be marketed as a growth tonic for children, the blood piece supposedly for joint and bone health, and the bone piece supposedly for calcium deficiency and geriatric needs.[2][5][9] Early commercial activity in Russia between the 1930s and 1980s led to the production of an alcohol extract from deer antler velvet marketed under the Russian drug trade name Pantocrin (also pantocrine or pantokrin).[10][11]
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