In an ovalbumin sensitized mouse model, 4 weeks of Velvet Antler at 2.5-10mg total (weight of mice not given, assuming 20g this equals 125-500mg/kg or 10-40mg/kg for humans) was able to reduce total Immunoglobulin E (IgE) and Ovalbumin-specific IgE at 14, 21, and 28 days.[21] When challenged with methacholine and subsequently having their airway power measured, it appeared that Velvet Antler exert anti-asthmatic effects in regards to allergies.[21] 

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Elk velvet antlers have been shown to contain chondroitin sulfate. This has a growth-promoting effect on cells throughout the body, which helps with recovery. This includes cells in the gut. It is believed that cartilage proteoglycans regulate water retention and differentiation and proliferation of chondrocytes inside cartilage tissue. Four types of collagen (I, II, III, and X) have also been identified in deer antlers. The collagen may provide benefits including rebuilding damaged parts of the GI tract, skin and joints. This might be beneficial for preventing or helping to treat leaky gut syndrome, which contributes to widespread symptoms.
Russian and Japanese researchers have conducted experiments using deer antler extract and found that it appears to lower blood pressure in both human subjects and laboratory animals. A series of clinical case studies (Albov, 1969) were conducted in which the effects of Pantocrin on cardiac patients were assessed. In one test involving 32 subjects with high blood pressure caused by cardiac disease, early onset menopause or obesity, blood pressure was lowered in 81% of patients. In another study involving 13 patients with hypotension caused by disorders of heart muscle activity, blood pressure was lowered for 84% of patients.
Deer antler velvet is rich in insulin-like growth factor 1 (IGF-1) which is a growth hormone produced naturally in the liver as a response to human growth hormone (HGH) stimulation. This is a key factor in how deer antler velvet can help to promote muscle growth. IGF-1 works on the body by promoting the growth of healthy, lean skeletal muscles. This growth of healthy muscle mass can be influenced by IGF-1's tendency to increase muscle protein and muscle DNA content. There is evidence to suggest that IGF-1 acts on muscle tissue by promoting protein synthesis and the proliferation of satellite cells, both of which result in skeletal muscle growth due to the enlargement of the muscle cells.
Its got a bunch of stuff in it, don't miss that link above about the constituents. But, overall it contains a large amount of peptides and minerals that work synergistically with unique compounds such as hyaluronic acid and growth factors to elicit many of the effects and results. Firstly we will outline the most scientifically backed uses of deer antler velvet. Read on and make your own conclusions from the evidence supplied in the rest of this article.
"Unlike steroids, which are small, cholesterol-based hormones, protein-based hormones or growth factors can easily be destroyed," he wrote in an email. Cohen guesses that even if you consume high levels of IGF-1, most if not all of the substance would be destroyed after hitting the acid in our stomach and before entering the blood system, which is how compounds we ingest reach the muscles. "This is also why you have to inject insulin instead of just eating insulin pills," he added.
My name is Michael Morabe and I’ve been an avid and addict of sand and indoor volleyball. I’m 27 years old and after getting back into volleyball 2 years ago, I realized I needed to lose weight. I just played more and more, shedding weight pretty rapidly, but after I lost about 35-40 pounds, I couldn’t do much more without starting to diet. The added problem was my recovery after playing so much during a week whether it be pick up or tournaments.

The latest and greatest performance enhancer, if you've been living under a rock, is deer antler velvet. On the surface, it seems like it could make sense. The coating on the antlers of young male deer that contribute to the growth of that part of their body could help athletes. First, the NFL prohibited Oakland Raiders coach Hue Jackson from endorsing it. Now, according to SI.com, Major League Baseball is warning players about using it.
Keeping true to our original Deer Antler Spray formula, Deer Antler Velvet Extract HERS is all-natural and contains the same amount of Deer Antler Velvet as the original, coming to us straight from red deer in New Zealand. Like the original, our new product is high in the growth hormone IGF-1. This new spray, however, is testosterone free and contains: collagen type II, biotin, green tea, and epimedium, all of which have benefits specially geared toward female athletes. Epimedium, known in Chinese medicine as “yin yang huo”, has the same effect as estrogen, can increase libido, and produce osteoblasts, the cells that secretes the matrix for bone formation. This promotes strong bones, and aids in the prevention of osteoporosis. Collagen, is a protein that forms the strong, flexible white fibers of the body's bone, cartilage, and connective tissue, and is vital for tissue regeneration. Biotin can speed up metabolism, improve glucose levels, and improve brittle nails. Green tea, is one of nature's most powerful antioxidants, and has been linked to cancer prevention, Alzheimer's prevention, the prevention of obesity, and countless other health benefits.
We have been in the health and fitness industry for almost 2 decades and have worked with many professional athletes as well as amateurs who used our products to help them perform at their best. We know how important it is to provide our customers with the best products on the market. We take great pride in our supplements and do not try to cut costs by using small dosages and fillers as many other companies do. When you purchase from us you can be absolutely confident you are getting the best quality and safest supplements you can find.
A systemic review on human interventions[25] makes note of a study conducted on patients of osteoarthritis (Edelman et al. 2000; cannot be located online) which found improvements in joint pain symptoms relative to baseline in the Velvet Antler group and not placebo, although a lack of information on blinding and randomization precludes results that can be drawn from this study.
It is difficult to analyze the quality of Deer Antler Velvet Spray’s ingredients due to their largely untested nature. Deer velvet contains glucosamine and chondroitin, two key chemicals in the body’s joint health processes that our panel of experts highly recommends. It may also increase estrogen production in the body, which can be both good and bad. In some that may be helpful for correcting existing hormonal imbalances, for others it may create them.
New Zealand research reports that although the mechanism is unknown, deer antler velvet shows strong anti-inflammatory effects. Recent clinical tests suggest oral ingestion of glycosaminoglycan-peptide complex, or components such as chondroitin sulfate and glucosamine sulfate — both found in deer antler velvet — may help stimulate cartilage repair.
The IGF-1 found in deer antler spray is derived from deer antler velvet, the tissue found inside the deer's antlers before they fully harden. Since deer antlers grow incredibly fast, it is not surprising that the horns are rich in IGF-1. This is a naturally-occurring form of IGF-1, meaning it is not made in a lab. As a result, deer antler velvet is considered a dietary supplement by the Food and Drug Administration, and unlike synthesized drugs, the product does have to be proven safe or effective before it's sold to the public.
When antlers fall off, they leave wounds that heal quickly, without forming a scar. Researchers have found that velvet antler contains substances that encourage healing, and could be of use to humans. Of particular interest are 3 hormones known to promote growth of skin tissue: insulin-like growth factor (IGF-1), epidermal growth factor (EGF) and transforming growth factor-β1 (TGF-β1). In a recent study, an ointment made from velvet antler, containing these compounds, enhanced healing when applied to the skin of rats. IGF-1 was a hot topic in the media in the winter of 2013 when a football player, Ray Lewis, was accused of using a banned spray containing IGF-1.

Although the site states that this product shouldn’t cause ill side effects, most western medical practitioners would dissuade you from taking this because the components found in deer antlers haven’t been approved by the FDA. More importantly, IGF-1 has been proven unstable. So, it’s best to speak to your physician, especially when you’re currently taking other forms of medication.

In Russia, Korea and China, deer antler velvet is widely used by athletes to enhance performance. In the United States, more and more athletes are looking to deer antler velvet as a training aid, a promoter of recovery after physical activity and injury, and possibly an injury preventative. Deer velvet could improve athletic performance in many ways, for example by assisting strength and endurance, by supporting the oxygen-carrying capacity of the blood, by facilitating minor tissue damage, and by boosting the immune system.
In a randomized, placebo controlled test in 2004, researchers at the University of Alberta, Canada, placed 18 males from the Edmonton Police Force into a 9 week strength training program. The results showed that deer antler velvet increased the strength and endurance of the subjects relative to the control group. The researchers found that use of deer antler velvet significantly increased blood plasma testosterone levels. 
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